This newly method expected to solve the problem on high-order interactions among SNPs with a huge number of genetic effects that made the LASSO failing to work under the old computation method. The article published narrated how Forward LASSO analysis can shrink most of genetic effects to be zeros stage by stage. However, simulation demonstrates that the newly introduced method could be used instead of the LASSO method for full model in mapping high-order interactions. Application of forward LASSO method is provided to Wide Association Study (GWAS) for carcass (beef) traits quality study.

For more information, contact at Briefings in Bioinformatics:
http://bib.oxfordjournals.org/search?fulltext=Forward+LASSO+the+Method+for+Meat+(Beef)+Quality+Traits+Study&submit=yes&x=8&y=12